In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China

Abstract Purpose Bifidobacterium is an important probiotic used in food and medicine production. The properties of bifidobacteria are strain specific, so it necessary to evaluate the isolated from specific populations, especially when developing products suitable for populations. objective this study was potential safety healthy Uyghur infants northwestern China. Methods In study, antimicrobial activity, antibiotic sensitivity, hemolytic, acid bile tolerance, hydrophobicity, co-aggregation, auto-aggregation, antioxidant activity were evaluated. Results Based on antagonistic spectrum against seven intestinal pathogenic bacteria, 14 excellent strains initially selected. Among strains, four (BF17-4, BF52-1, BF87-3, BF88-5) superior Lactobacillus rhamnosus GG cell surface hydrophobicity auto-aggregation percentages close co-aggregation with Escherichia coli EPEC O127: K63 (CICC 10411). activities each varied components. Most sensitive all antimicrobials tested, except kanamycin amikacin. Conclusion BF17-4 BF52-1 good candidates further vivo studies functional foods.